SCHEMBL6549241

SCHEMBL6549241

COc1cc(OC)c(CON)c(OC)c1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 8/20 0.53
AGXT P21549 4/20 0.47
CYP1A2 P05177 1/20 0.43
ALDH1A1 P00352 2/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CYP3A4 P08684 2/20 0.41
USP2 O75604 1/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ERN1 O75460 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7952922 0.82 ALDH1A1 (0.46) CYP1A2ALDH1A1CA12CA1CA2
SCHEMBL4002789 0.82 ALDH1A1 (0.46) CYP1A2ALDH1A1CA12CA1CA2
SCHEMBL7952918 0.78 ALDH1A1 (0.42) CYP1A2ALDH1A1CA12CA1CA2
SCHEMBL442070 0.77 CYP1A2 (0.50) CYP1A2ALDH1A1CA12CA1CA2
SCHEMBL2090427 0.77 ALDH1A1 (0.40) CYP1A2ALDH1A1CA12CA1CA2
SCHEMBL2096172 0.77 ALDH1A1 (0.50) CYP1A2ALDH1A1CA12CA1CA2
Hydrochloric Acid SCHEMBL1093815 0.76 CYP1A2 (0.48) IDO1CYP1A2ALDH1A1CA12CA1
SCHEMBL2090422 0.75 ERN1 (0.42) CYP1A2ALDH1A1CA12CA1CA2
SCHEMBL5185794 0.75 ALDH1A1 (0.48) CYP1A2ALDH1A1CA12CA1CA2
SCHEMBL1049672 0.74 TAAR1 (0.64) CYP1A2CYP3A4MAPK1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1236717-B1 OXIME O-ETHER COMPOUNDS AND FUNGICIDES FOR AGRICULTURAL AND HORTICULTURAL USE NIPPON SODA CO (JP) 2004-02-04 EP disclosed
US-6589967-B1 Fungicide for agricultural and horticultural use comprising the compound as the active ingredient. agricultural plant protection chemicals have been used for controlling plant diseases. NIPPON SODA CO. LTD. (JP) 2003-07-08 US disclosed
EP-1236717-A1 OXIME O-ETHER COMPOUNDS AND FUNGICIDES FOR AGRICULTURAL AND HORTICULTURAL USE NIPPON SODA CO., LTD. (JP) 2002-09-04 EP disclosed