SCHEMBL20904336

SCHEMBL20904336

Fc1cccc(N(c2ccc3c4ccccc4n(-c4ccccc4)c3c2)c2cccc3c2c2ccccc2n3-c2ccccc2)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
JAK2 O60674 1/20 0.40
JAK3 P52333 1/20 0.40
REN P00797 3/20 0.36
PER2 O15055 1/20 0.34
MAT2A P31153 2/20 0.33
RXFP1 Q9HBX9 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
METAP2 P50579 2/20 0.32
HTR7 P34969 1/20 0.31
ABCG2 Q9UNQ0 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20904309 0.95 KDM4E (0.40) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL20904311 0.95 KDM4E (0.40) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL20904312 0.94 KDM4E (0.38) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL20904335 0.94 KDM4E (0.37) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL20904363 0.92 JAK2 (0.46) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL20904310 0.92 KDM4E (0.43) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL20904500 0.92 JAK2 (0.41) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL20904318 0.92 KDM4E (0.44) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL20904406 0.92 KDM4E (0.47) KDM4EATML3MBTL1JAK2JAK3
SCHEMBL26539096 0.92 L3MBTL1 (0.50) KDM4EATML3MBTL1JAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10937967-B2 Amine-based compound and organic light-emitting device including the amine-based compound SAMSUNG DISPLAY CO., LTD. (KR) 2021-03-02 US disclosed
US-20190115543-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE AMINE-BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10937967-B2 Amine-based compound and organic light-emitting device including the amine-based compound AOC2, AOC1, SAT1 KDM4E 495/4885ATM 792/4885L3MBTL1 665/4885
US-20190115543-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE AMINE-BASED COMPOUND AOC2, AOC1, SAT1 KDM4E 495/4885ATM 792/4885L3MBTL1 665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.