SCHEMBL20904376

SCHEMBL20904376

Fc1ccc2c3ccc(N(c4ccccc4)c4ccc5c6ccccc6n(-c6ccccc6)c5c4)cc3n(-c3ccccc3)c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.50
KDM4E B2RXH2 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
JAK2 O60674 1/20 0.43
JAK3 P52333 1/20 0.43
MAT2A P31153 2/20 0.42
CYP1A2 P05177 2/20 0.36
METAP2 P50579 1/20 0.36
REN P00797 3/20 0.34
MAPK8 P45983 2/20 0.34
G6PD P11413 1/20 0.34
MPI P34949 1/20 0.34
PHOSPHO1 Q8TCT1 1/20 0.34
KDR P35968 1/20 0.33
CCR3 P51677 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20904378 0.95 ATM (0.47) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL20904461 0.95 ATM (0.47) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL20904496 0.94 ATM (0.53) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL20904456 0.93 ATM (0.46) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL20904343 0.93 ATM (0.46) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL20904436 0.93 ATM (0.47) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL20904497 0.92 KDM4E (0.47) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL20904308 0.92 ATM (0.50) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL20904305 0.92 JAK2 (0.49) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL22989359 0.91 KDM4E (0.60) ATMKDM4EL3MBTL1MAT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10937967-B2 Amine-based compound and organic light-emitting device including the amine-based compound SAMSUNG DISPLAY CO., LTD. (KR) 2021-03-02 US disclosed
US-20190115543-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE AMINE-BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10937967-B2 Amine-based compound and organic light-emitting device including the amine-based compound AOC2, AOC1, SAT1 ATM 792/4885KDM4E 495/4885L3MBTL1 665/4885
US-20190115543-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE AMINE-BASED COMPOUND AOC2, AOC1, SAT1 ATM 792/4885KDM4E 495/4885L3MBTL1 665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.