SCHEMBL20904456

SCHEMBL20904456

Fc1ccc2c(c1)c1ccc(N(c3ccccc3)c3ccc4c(c3)c3ccccc3n4-c3ccccc3)cc1n2-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.46
JAK2 O60674 1/20 0.46
JAK3 P52333 1/20 0.46
KDM4E B2RXH2 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP1A2 P05177 2/20 0.39
METAP2 P50579 2/20 0.39
MAT2A P31153 2/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.36
PER2 O15055 2/20 0.34
CRY1 Q16526 2/20 0.34
CRY2 Q49AN0 2/20 0.34
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
REN P00797 3/20 0.33
MPI P34949 2/20 0.32
PHOSPHO1 Q8TCT1 2/20 0.32
MAPK8 P45983 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20904343 1.00 ATM (0.46) ATMJAK2JAK3KDM4EL3MBTL1
SCHEMBL20904461 0.99 ATM (0.47) ATMJAK2JAK3KDM4EL3MBTL1
SCHEMBL20904344 0.97 JAK2 (0.48) ATMJAK2JAK3KDM4EL3MBTL1
SCHEMBL20904305 0.96 JAK2 (0.49) ATMJAK2JAK3KDM4EL3MBTL1
SCHEMBL20904455 0.95 KDM4E (0.46) ATMJAK2JAK3KDM4EL3MBTL1
SCHEMBL20904342 0.95 KDM4E (0.46) ATMJAK2JAK3KDM4EL3MBTL1
SCHEMBL20904434 0.95 JAK2 (0.48) ATMJAK2JAK3KDM4EL3MBTL1
SCHEMBL20904454 0.95 ATM (0.49) ATMJAK2JAK3KDM4EL3MBTL1
SCHEMBL20904457 0.94 KDM4E (0.44) ATMJAK2JAK3KDM4EL3MBTL1
SCHEMBL20904376 0.93 ATM (0.50) ATMJAK2JAK3KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10937967-B2 Amine-based compound and organic light-emitting device including the amine-based compound SAMSUNG DISPLAY CO., LTD. (KR) 2021-03-02 US disclosed
US-20190115543-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE AMINE-BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10937967-B2 Amine-based compound and organic light-emitting device including the amine-based compound AOC2, AOC1, SAT1 ATM 792/4885JAK2 3002/4885JAK3 2419/4885
US-20190115543-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE AMINE-BASED COMPOUND AOC2, AOC1, SAT1 ATM 792/4885JAK2 3002/4885JAK3 2419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.