Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | NEK2 | P51955 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20904511 | 0.83 | ALDH1A1 (0.44) | SRCKDM4EALDH1A1LMNATP53 | |
| SCHEMBL20904524 | 0.80 | KDM4E (0.37) | SRCKDM4EALDH1A1LMNATP53 | |
| SCHEMBL20904510 | 0.77 | SRC (0.36) | SRCKDM4EALDH1A1LMNATP53 | |
| SCHEMBL20898048 | 0.77 | SRC (0.36) | SRCKDM4EALDH1A1LMNATP53 | |
| SCHEMBL22341667 | 0.77 | SRC (0.38) | SRCKDM4EALDH1A1LMNATP53 | |
| SCHEMBL20898042 | 0.75 | SRC (0.38) | SRCALDH1A1HSD17B10TDP1CA12 | |
| SCHEMBL22389359 | 0.74 | PNMT (0.39) | SRCKDM4EALDH1A1TP53GAA | |
| SCHEMBL20898588 | 0.74 | SRC (0.36) | SRCKDM4EALDH1A1LMNATP53 | |
| SCHEMBL22341730 | 0.74 | SRC (0.36) | SRCKDM4EMAPTCA12CA1 | |
| SCHEMBL20898356 | 0.74 | SRC (0.40) | SRCKDM4EALDH1A1TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200276102-A1 | SPECIFIC 7-AMINO-1,2,3,4-TETRAHYDROQUINOLINES, METHOD, AND COMPOSITION | L'OREAL (FR) | 2020-09-03 | — | — | US | disclosed |
| WO-2019072697-A1 | SPECIFIC 7-AMINO-1,2,3,4-TETRAHYDROQUINOLINES, METHOD, AND COMPOSITION | L'OREAL (FR) | 2019-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200276102-A1 | SPECIFIC 7-AMINO-1,2,3,4-TETRAHYDROQUINOLINES, METHOD, AND COMPOSITION | KRT18, TUBA1C, TPM4 | SRC 2302/4885KDM4E 217/4885ALDH1A1 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.