Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IL1B | P01584 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19010223 | 0.88 | TSHR (0.39) | ADORA2AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL19847495 | 0.88 | TSHR (0.39) | ADORA2AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL19010229 | 0.85 | TSHR (0.46) | ADORA2AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL16380407 | 0.84 | TSHR (0.44) | ADORA2AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL18123342 | 0.82 | THRB (0.38) | ADORA2AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL20089021 | 0.79 | THRB (0.41) | ADORA2AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL20089038 | 0.78 | ALDH1A1 (0.33) | ADORA2AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL20089025 | 0.78 | ALDH1A1 (0.36) | ADORA2AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL20089028 | 0.78 | ALDH1A1 (0.43) | ADORA2AMEN1NPC1RAB9AKMT2A | |
| SCHEMBL18123336 | 0.78 | TSHR (0.41) | ADORA2AMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190112413-A1 | SILICON-CONTAINING COMPOUND, URETHANE RESIN, STRETCHABLE FILM, AND METHOD FOR FORMING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190112413-A1 | SILICON-CONTAINING COMPOUND, URETHANE RESIN, STRETCHABLE FILM, AND METHOD FOR FORMING THE SAME | PNISR, OR10J3, OXSR1 | ADORA2A 3694/4885MEN1 1624/4885NPC1 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.