Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | BRD1 | O95696 | 2/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.33 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29640227 | 1.00 | MMP1 (0.36) | MMP1ADAM17ALOX5MEN1KMT2A | |
| SCHEMBL21148935 | 0.92 | MMP1 (0.34) | MMP1ADAM17ALOX5MEN1KMT2A | |
| SCHEMBL20907575 | 0.92 | MMP1 (0.34) | MMP1ADAM17ALOX5MEN1KMT2A | |
| SCHEMBL21112302 | 0.89 | MEN1 (0.39) | MMP1ADAM17ALOX5MEN1KMT2A | |
| SCHEMBL21112298 | 0.89 | MEN1 (0.39) | MMP1ADAM17ALOX5MEN1KMT2A | |
| SCHEMBL29640198 | 0.83 | AAK1 (0.34) | MEN1KMT2ACTSSAAK1TACR1 | |
| SCHEMBL23114826 | 0.82 | TACR1 (0.37) | MMP1MEN1KMT2ACTSSAAK1 | |
| SCHEMBL20908217 | 0.82 | TACR1 (0.37) | MMP1MEN1KMT2ACTSSAAK1 | |
| SCHEMBL29640270 | 0.81 | CTSS (0.37) | MEN1KMT2ACTSSAAK1TACR1 | |
| SCHEMBL20907560 | 0.81 | MEN1 (0.37) | MEN1KMT2ACTSSAAK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019075291-A1 | 1-BENZYL-2-IMINO-4-PHENYL-5-OXOIMIDAZOLIDINE DERIVATIVES AS HIV PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2019-04-18 | — | — | WO | disclosed |