SCHEMBL20909407

SCHEMBL20909407

c1ccc(-c2c3ccccc3c(-c3ccc4c(c3)-c3ccccc3-c3ccccc3-c3ccccc3-4)c3ccc(-c4nccc5c4sc4ccccc45)cc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.38
LIMK1 P53667 2/20 0.33
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
PRKDC P78527 1/20 0.32
MEN1 O00255 1/20 0.31
APAF1 O14727 1/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
XBP1 P17861 1/20 0.31
PTBP1 P26599 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
GALK1 P51570 1/20 0.31
BLM P54132 1/20 0.31
SMAD3 P84022 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11941210 0.92 LIMK1 (0.38) ALOX5LIMK1TNKSTNKS2MAPT
SCHEMBL11941214 0.91 LIMK1 (0.40) ALOX5LIMK1TNKSTNKS2MAPT
SCHEMBL20909409 0.90 HTR2B (0.41) ALOX5PRKDCMAPT
SCHEMBL20909410 0.83 LIMK1 (0.45) LIMK1
SCHEMBL11941219 0.83 TDO2 (0.42) ALOX5LIMK1TNKSTNKS2NPC1
SCHEMBL11030653 0.83 HTR2B (0.45) ALOX5LIMK1MEN1NPC1LMNA
SCHEMBL30606988 0.83 HTR2B (0.45) ALOX5LIMK1MEN1NPC1LMNA
SCHEMBL11941212 0.82 HTR2B (0.44) ALOX5LIMK1MEN1NPC1LMNA
SCHEMBL11941216 0.82 ALOX5 (0.41) ALOX5LIMK1PRKDCLMNAMAPT
SCHEMBL11941221 0.82 GPR3 (0.39) ALOX5LIMK1TNKSTNKS2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11201290-B2 Tetraphenylene anthracene compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-12-14 US disclosed
US-20190115541-A1 TETRAPHENYLENE ANTHRACENE COMPOUNDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190115541-A1 TETRAPHENYLENE ANTHRACENE COMPOUNDS TRPA1, SLC29A2, XPOT ALOX5 2952/4885LIMK1 3095/4885TNKS 745/4885
US-11201290-B2 Tetraphenylene anthracene compounds TRPA1, SLC29A2, XPOT ALOX5 2952/4885LIMK1 3095/4885TNKS 745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.