SCHEMBL20909421

SCHEMBL20909421

c1ccc2c(c1)-c1ccccc1-c1cnc(-c3c4ccccc4c(-c4cccc5ccccc45)c4ccccc34)cc1-c1ccccc1-2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
DHFR P00374 1/20 0.40
GSK3B P49841 1/20 0.38
CDK5 Q00535 1/20 0.38
CDK5R1 Q15078 1/20 0.38
CYP11B2 P19099 3/20 0.37
CYP11B1 P15538 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 2/20 0.37
MAPK1 P28482 2/20 0.37
HSD17B10 Q99714 2/20 0.37
NPC1 O15118 2/20 0.37
KDM4E B2RXH2 2/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 1/20 0.37
CASP1 P29466 1/20 0.37
HIF1A Q16665 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20909418 0.88 ENPP1 (0.43) ALDH1A1HSD17B10KDM4ECA12CA9
SCHEMBL24662854 0.87 NPC1 (0.51) MEN1KMT2ADHFRGSK3BCDK5
SCHEMBL20909339 0.86 TNF (0.39) MEN1KMT2AGSK3BALDH1A1HPGD
SCHEMBL20909419 0.80 DHFR (0.44) DHFRCYP11B2CYP11B1ALDH1A1HPGD
SCHEMBL15158541 0.79 MEN1 (0.44) MEN1KMT2ADHFRCYP11B2CYP11B1
SCHEMBL20909340 0.78 CYP17A1 (0.41) DHFRCYP11B2CYP11B1KDM4E
SCHEMBL1102838 0.78 NPC1 (0.43) MEN1KMT2AGSK3BCDK5CDK5R1
SCHEMBL702934 0.78 ALDH1A1 (0.50) MEN1KMT2ADHFRGSK3BALDH1A1
SCHEMBL29407412 0.78 ALDH1A1 (0.50) MEN1KMT2ADHFRGSK3BALDH1A1
SCHEMBL17227621 0.77 KDM4E (0.58) MEN1KMT2ADHFRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11201290-B2 Tetraphenylene anthracene compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-12-14 US disclosed
US-20190115541-A1 TETRAPHENYLENE ANTHRACENE COMPOUNDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190115541-A1 TETRAPHENYLENE ANTHRACENE COMPOUNDS TRPA1, SLC29A2, XPOT MEN1 1625/4885KMT2A 3313/4885DHFR 3124/4885
US-11201290-B2 Tetraphenylene anthracene compounds TRPA1, SLC29A2, XPOT MEN1 1625/4885KMT2A 3313/4885DHFR 3124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.