Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215130 | 0.83 | CYP1A2 (0.41) | ALDH1A1CYP3A4SRD5A1FAAHNOTUM | |
| SCHEMBL20883905 | 0.81 | ACHE (0.41) | ACHECA1CA2CYP3A4 | |
| SCHEMBL1950847 | 0.81 | GHSR (0.50) | HSD11B1GHSRFAAH | |
| SCHEMBL9218363 | 0.79 | FAAH (0.44) | ACHECA1CA2ALDH1A1CYP3A4 | |
| SCHEMBL5889332 | 0.79 | FAAH (0.44) | ACHECA1CA2ALDH1A1CYP3A4 | |
| SCHEMBL25554146 | 0.76 | CYP1A2 (0.41) | ACHECA1CA2ALDH1A1CYP3A4 | |
| SCHEMBL22860684 | 0.75 | ACHE (0.39) | ACHECA1CA2MCHR1ALDH1A1 | |
| SCHEMBL22860677 | 0.75 | MCHR1 (0.38) | ACHECA1CA2MCHR1ALDH1A1 | |
| SCHEMBL20890008 | 0.75 | ACHE (0.43) | ACHECA1CA2MCHR1ALDH1A1 | |
| SCHEMBL15803039 | 0.75 | MCHR1 (0.47) | ACHECA1CA2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074979-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | GIRAFPHARMA, LLC (US) | 2019-04-18 | — | — | WO | disclosed |