Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20909692 | 0.85 | LMNA (0.52) | HTR2AHTR2CHTR2BLMNAALDH1A1 | |
| SCHEMBL20909691 | 0.85 | LMNA (0.52) | HTR2AHTR2CHTR2BLMNAALDH1A1 | |
| SCHEMBL13102476 | 0.79 | LMNA (0.47) | FYNLMNAALDH1A1GRIN2BKDM4E | |
| SCHEMBL15127496 | 0.77 | FYN (0.42) | FYNLMNAALDH1A1KDM4ESRD5A1 | |
| SCHEMBL20892033 | 0.76 | HTR2A (0.45) | FYNHTR2AHTR2CHTR2BLMNA | |
| SCHEMBL20883972 | 0.76 | ACHE (0.43) | FYNALDH1A1GRIN2BKDM4ENPSR1 | |
| SCHEMBL13102446 | 0.76 | LMNA (0.44) | HTR2ALMNAALDH1A1GRIN2BKDM4E | |
| Hydrochloric Acid SCHEMBL9342934 | 0.74 | HTR2C (0.44) | HTR2AHTR2CHTR2BLMNAGRIN2B | |
| SCHEMBL14875712 | 0.74 | KDM4E (0.46) | FYNHTR2ALMNAALDH1A1GRIN2B | |
| SCHEMBL80428 | 0.74 | ACHE (0.47) | HTR2AHTR2CHTR2BALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074979-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | GIRAFPHARMA, LLC (US) | 2019-04-18 | — | — | WO | disclosed |