Sugi Predict

Sugi Predict / Compounds / SCHEMBL80428

SCHEMBL80428

SCHEMBL80428

Cc1ccc2c(c1)CC(C)C2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 2/20 0.47
▸ HTR2C P28335 3/20 0.39
▸ HTR2A P28223 1/20 0.39
▸ HTR2B P41595 1/20 0.39
▸ METAP1 P53582 1/20 0.38
▸ ALDH1A1 P00352 2/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ PKM P14618 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ SLC6A2 P23975 1/20 0.37
▸ SLC6A4 P31645 1/20 0.37
▸ SLC6A3 Q01959 1/20 0.37
▸ SRD5A1 P18405 2/20 0.37
▸ CYP1A2 P05177 1/20 0.36
▸ CYP2A6 P11509 1/20 0.36
▸ AADAT Q8N5Z0 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31236154 1.00 ACHE (0.47) ACHEHTR2CHTR2AHTR2BMETAP1
SCHEMBL30930042 1.00 ACHE (0.47) ACHEHTR2CHTR2AHTR2BMETAP1
SCHEMBL27246033 1.00 ACHE (0.47) ACHEHTR2CHTR2AHTR2BMETAP1
Hydrochloric Acid SCHEMBL31426377 0.98 ACHE (0.46) ACHEHTR2CHTR2AHTR2BMETAP1
Alcohol SCHEMBL23531368 0.90 TRPM5 (0.41) ACHEHTR2CHTR2AHTR2BMETAP1
SCHEMBL597666 0.83 SRD5A1 (0.42) ACHEHTR2CHTR2AHTR2BALDH1A1
SCHEMBL79036 0.83 ALDH1A1 (0.42) ACHEHTR2CHTR2AHTR2BALDH1A1
SCHEMBL29619884 0.82 ACHE (0.44) ACHEHTR2CHTR2AHTR2BMETAP1
SCHEMBL294181 0.79 CA1 (0.50) ACHEMETAP1ALDH1A1MAPTAADAT
SCHEMBL22271487 0.79 ACHE (0.41) ACHEHTR2CHTR2AHTR2BMETAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4583708-A1 ARTHROPOD CONTROL COMPOSITIONS Firmenich SA (CH) 2025-07-16 — — EP claimed
CN-119451942-A Method for producing biguanide salts and triazines 安道麦阿甘有限公司 2025-02-14 — — CN claimed
CN-119451939-A Crystal form of indenofloxacin, preparation method and application thereof 安道麦阿甘有限公司 2025-02-14 — — CN claimed
WO-2024084006-A1 ARTHROPOD CONTROL COMPOSITIONS FIRMENICH SA (CH) 2024-04-25 — — WO claimed
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH & CIE (CH) 2026-03-12 — — US disclosed
US-20260002097-A1 TEXTILE ARTICLES FOR TUMBLE-DRYING FIRMENICH & CIE (CH) 2026-01-01 — — US disclosed
US-12414937-B2 Local and regional anesthesia and analgesia UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2025-09-16 — — US disclosed
US-20250268804-A1 FRAGRANCE COMPOSITIONS FIRMENICH SA (CH) 2025-08-28 — — US disclosed
EP-4583708-A1 ARTHROPOD CONTROL COMPOSITIONS Firmenich SA (CH) 2025-07-16 — — EP disclosed
US-12290591-B2 Fragrance compositions FIRMENICH SA (CH) 2025-05-06 — — US disclosed
CN-119451942-A Method for producing biguanide salts and triazines 安道麦阿甘有限公司 2025-02-14 — — CN disclosed
CN-119451939-A Crystal form of indenofloxacin, preparation method and application thereof 安道麦阿甘有限公司 2025-02-14 — — CN disclosed
CN-107847624-A Indane derivatives for malodor counteraction 弗门尼舍有限公司 2018-03-27 — — CN disclosed
US-20180037818-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2018-02-08 — — US disclosed
US-20170121633-A1 Fragrance Compositions Comprising Ionic Liquids THE PROCTER & GAMBLE COMPANY 2017-05-04 — — US disclosed
US-20160362631-A1 Fragrance Fixatives and Compositions Comprising Thereof THE PROCTER & GAMBLE COMPANY 2016-12-15 — — US disclosed
US-8129002-B2 Compounds for use in liquid crystal media MERCK PATENT GMBH (DE) 2012-03-06 — — US disclosed
US-8124610-B2 Sodium channel inhibitors ICAGEN INC. (US) 2012-02-28 — — US disclosed
US-7531106-B2 Mesogenic compounds, medium for electro-optical displays and electro-optical display MERCK PATENT GMBH (DE) 2009-05-12 — — US disclosed
US-20090023740-A1 SODIUM CHANNEL INHIBITORS ICAGEN (US) 2009-01-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170121633-A1 Fragrance Compositions Comprising Ionic Liquids CUTA, TRPA1, POLR1C ACHE 1903/4885HTR2C 848/4885HTR2A 663/4885
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION CNOT9, MSL1, MT-CO2 ACHE 345/4885HTR2C 1773/4885HTR2A 2456/4885
US-20090023740-A1 SODIUM CHANNEL INHIBITORS TRPV1, SCN1A, SCN2A ACHE 442/4885HTR2C 852/4885HTR2A 1260/4885
US-20250268804-A1 FRAGRANCE COMPOSITIONS PLIN5, ELOVL5, ALOX5 ACHE 178/4885HTR2C 2977/4885HTR2A 1390/4885
US-20260002097-A1 TEXTILE ARTICLES FOR TUMBLE-DRYING ETV1, TRPC5, F5 ACHE 3268/4885HTR2C 615/4885HTR2A 1009/4885
US-12414937-B2 Local and regional anesthesia and analgesia OPRL1, OPRK1, OPRM1 ACHE 12/4885HTR2C 1072/4885HTR2A 543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.