Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840356 | 0.86 | MEN1 (0.45) | MEN1KMT2AOPRM1OPRD1RAB9A | |
| SCHEMBL20890507 | 0.84 | CHRNB2 (0.44) | TSHRCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL20890082 | 0.84 | ADORA2A (0.42) | MEN1KMT2AOPRM1OPRD1SMN1; SMN2 | |
| SCHEMBL6840494 | 0.82 | RAB9A (0.43) | MEN1KMT2AOPRM1OPRD1RAB9A | |
| SCHEMBL10305062 | 0.79 | RAB9A (0.41) | MEN1KMT2AOPRM1OPRD1RAB9A | |
| SCHEMBL3508756 | 0.78 | MEN1 (0.49) | MEN1KMT2AOPRM1OPRD1RAB9A | |
| SCHEMBL12788604 | 0.78 | MEN1 (0.42) | MEN1KMT2AOPRM1OPRD1RAB9A | |
| SCHEMBL14547221 | 0.78 | RAB9A (0.40) | MEN1KMT2AOPRM1OPRD1RAB9A | |
| SCHEMBL9512579 | 0.77 | EGFR (0.42) | MEN1KMT2AOPRM1OPRD1RAB9A | |
| SCHEMBL676887 | 0.76 | SMN1; SMN2 (0.47) | MEN1KMT2ARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074979-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | GIRAFPHARMA, LLC (US) | 2019-04-18 | — | — | WO | disclosed |