Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12331332 | 0.86 | TDP1 (0.46) | SMN1; SMN2TDP1MAPTLIN28AKMT2A | |
| SCHEMBL2186737 | 0.85 | TRPM8 (0.52) | SMN1; SMN2TDP1MAPTLIN28AMEN1 | |
| SCHEMBL2755875 | 0.84 | HIF1A (0.59) | SMN1; SMN2TDP1MEN1KMT2AHIF1A | |
| SCHEMBL4676290 | 0.83 | HTR2C (0.49) | SMN1; SMN2TDP1MAPTLIN28AMEN1 | |
| SCHEMBL12207230 | 0.83 | HIF1A (0.48) | SMN1; SMN2TDP1MAPTLIN28AMEN1 | |
| SCHEMBL21742039 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2TDP1MAPTLIN28AMEN1 | |
| SCHEMBL427048 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2TDP1MAPTLIN28AKMT2A | |
| SCHEMBL6204342 | 0.81 | KDM4E (0.52) | SMN1; SMN2TDP1MAPTLIN28AKMT2A | |
| SCHEMBL15170931 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2TDP1MAPTLIN28AMEN1 | |
| SCHEMBL10875090 | 0.80 | MEN1 (0.46) | SMN1; SMN2TDP1MAPTLIN28AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180007904-A1 | Pesticidal Active Mixtures Comprising Isoxazoline Compounds I | BASF SE (DE) | 2018-01-11 | — | — | US | disclosed |
| US-20170354636-A1 | METHODS FOR INHIBITING TUMORS AND DRUG RESISTANCE | SEQUOIA PHARMACEUTICALS INC (US) | 2017-12-14 | — | — | US | disclosed |
| US-9770029-B2 | Pesticidal active mixtures comprising isoxazoline compounds I | BASF SE (DE) | 2017-09-26 | — | — | US | disclosed |
| US-20170042156-A1 | Pesticidal Active Mixtures Comprising Isoxazoline Compounds I | BASF SE (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20140087943-A1 | Pesticidal Active Mixtures Comprising Isoxazoline Compounds I | BASF SE (DE) | 2014-03-27 | — | — | US | disclosed |
| US-8563474-B2 | Pestcidal active mixtures comprising isoxazoline compounds I | BASF SE (DE) | 2013-10-22 | — | — | US | disclosed |
| US-20130060013-A1 | Compounds useful for treating neurodegenerative disorders | SATORI PHARMACEUTICALS, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-20110159107-A1 | Pesticidal Mixtures Comprising Isoxazoline Compounds II | BASF SE (DE) | 2011-06-30 | — | — | US | disclosed |
| US-20110118212-A1 | Pestcidal active mixtures comprising isoxazoline compounds I | BASF SE (DE) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110159107-A1 | Pesticidal Mixtures Comprising Isoxazoline Compounds II | PRDX1, PRDX2, PRDX5 | SMN1; SMN2 2069/4885TDP1 2621/4885MAPT 3866/4885 |
| US-20170042156-A1 | Pesticidal Active Mixtures Comprising Isoxazoline Compounds I | CHRM3, CHRM5, CACNA1C | SMN1; SMN2 4585/4885TDP1 4776/4885MAPT 3593/4885 |
| US-20170354636-A1 | METHODS FOR INHIBITING TUMORS AND DRUG RESISTANCE | HCCS, CYP2E1, CYP7A1 | SMN1; SMN2 4787/4885TDP1 3756/4885MAPT 4370/4885 |
| US-20110118212-A1 | Pestcidal active mixtures comprising isoxazoline compounds I | CHRM3, CHRM5, CHRM1 | SMN1; SMN2 4325/4885TDP1 4816/4885MAPT 3468/4885 |
| US-20180007904-A1 | Pesticidal Active Mixtures Comprising Isoxazoline Compounds I | CHRM3, CHRM5, CACNA1C | SMN1; SMN2 4585/4885TDP1 4776/4885MAPT 3593/4885 |
| US-20130060013-A1 | Compounds useful for treating neurodegenerative disorders | SNCA, HTT, CLN6 | SMN1; SMN2 7/4885TDP1 159/4885MAPT 4/4885 |
| US-20140087943-A1 | Pesticidal Active Mixtures Comprising Isoxazoline Compounds I | CHRM3, CHRM5, CACNA1C | SMN1; SMN2 4585/4885TDP1 4776/4885MAPT 3593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.