SCHEMBL20911129

SCHEMBL20911129

O=C(O)CCCCCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NO)C(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.56
▸ NOD1 Q9Y239 5/20 0.56
▸ FOLH1 Q04609 3/20 0.52
▸ EPHX2 P34913 2/20 0.47
▸ GNPAT O15228 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20911434 1.00 GLP1R (0.56) GLP1RNOD1FOLH1EPHX2GNPAT
SCHEMBL29322234 0.94 GLP1R (0.52) GLP1RNOD1FOLH1EPHX2
SCHEMBL16273259 0.93 NOD1 (0.59) GLP1RNOD1FOLH1EPHX2
SCHEMBL20910955 0.92 EPHX2 (0.50) GLP1RNOD1FOLH1EPHX2
SCHEMBL20910956 0.92 EPHX2 (0.50) GLP1RNOD1FOLH1EPHX2
SCHEMBL24173323 0.90 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2
SCHEMBL24173761 0.90 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2
SCHEMBL23157321 0.90 GLP1R (0.54) GLP1RNOD1FOLH1EPHX2
SCHEMBL23157341 0.90 GLP1R (0.54) GLP1RNOD1FOLH1EPHX2
SCHEMBL24174150 0.90 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190112348-A1 PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES NOVO NORDISK AS (DK) 2019-04-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190112348-A1 PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES IAPP, IDE, LIPE GLP1R 84/4885NOD1 3929/4885FOLH1 408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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