Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MASP2 | O00187 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL3167894 | 0.82 | CES2 (0.47) | MAPTHIF1ALMNAMEN1KMT2A | |
| SCHEMBL9420249 | 0.81 | LMNA (0.40) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| Hydroxyamine SCHEMBL11026948 | 0.79 | CES1 (0.54) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL31097912 | 0.78 | CES1 (0.58) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL2904552 | 0.78 | CES1 (0.58) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL637241 | 0.78 | CES1 (0.58) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL32681153 | 0.78 | CES1 (0.58) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL414466 | 0.78 | CES1 (0.58) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL7684 | 0.78 | CES1 (0.58) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL20912859 | 0.77 | CES2 (0.52) | MAPTLMNAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473625-B1 | PREPARATION METHOD FOR CHIRAL PYRROLOPYRIMIDINE COMPOUND | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2021-06-02 | — | — | EP | disclosed |
| US-10766901-B2 | Preparation method for chiral pyrrolopyrimidine compound | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2020-09-08 | — | — | US | disclosed |
| US-20190211021-A1 | Preparation Method For Chiral Pyrrolopyrimidine Compound | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
| EP-3473625-A1 | PREPARATION METHOD FOR CHIRAL PYRROLOPYRIMIDINE COMPOUND | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190211021-A1 | Preparation Method For Chiral Pyrrolopyrimidine Compound | DHPS, DPYD, MPHOSPH6 | MAPT 3431/4885KDM4E 2822/4885HIF1A 3144/4885 |
| US-10766901-B2 | Preparation method for chiral pyrrolopyrimidine compound | DHPS, DPYD, MPHOSPH6 | MAPT 3431/4885KDM4E 2822/4885HIF1A 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.