Cinnamaldehyde

Cinnamaldehyde

SCHEMBL20912968

CCCCCC=O.O=CC=Cc1ccccc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
LMNA P02545 2/20 0.60
TRPA1 O75762 1/20 0.60
ALOX5 P09917 1/20 0.60
MAPK1 P28482 1/20 0.60
TSHR P16473 3/20 0.48
TRPV1 Q8NER1 2/20 0.44
FAAH O00519 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
EGFR P00533 1/20 0.43
MAOB P27338 1/20 0.42
CCNB2 O95067 2/20 0.40
CDK1 P06493 2/20 0.40
CDK4 P11802 2/20 0.40
CCNB1 P14635 2/20 0.40
CCND1 P24385 2/20 0.40
CCNB3 Q8WWL7 2/20 0.40
HDAC3 O15379 1/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinnamaldehyde SCHEMBL20912967 1.00 ALDH1A1 (0.60) ALDH1A1LMNATRPA1ALOX5MAPK1
Cinnamaldehyde SCHEMBL26185633 0.88 ALDH1A1 (0.72) ALDH1A1LMNATRPA1ALOX5MAPK1
Cinnamaldehyde SCHEMBL28715783 0.83 ALDH1A1 (0.60) ALDH1A1LMNATRPA1ALOX5MAPK1
Cinnamaldehyde SCHEMBL28715784 0.83 ALDH1A1 (0.60) ALDH1A1LMNATRPA1ALOX5MAPK1
Benzaldehyde SCHEMBL28286279 0.82 TSHR (0.56) ALDH1A1LMNAMAPK1TSHRTRPV1
Octadecylamine SCHEMBL29196154 0.82 LMNA (0.58) ALDH1A1LMNATRPA1ALOX5MAPK1
Octadecylamine SCHEMBL29196155 0.82 LMNA (0.58) ALDH1A1LMNATRPA1ALOX5MAPK1
Cinnamaldehyde SCHEMBL28716525 0.81 ALDH1A1 (0.62) ALDH1A1LMNATRPA1ALOX5MAPK1
Cinnamaldehyde SCHEMBL5884331 0.81 LMNA (0.62) ALDH1A1LMNATRPA1ALOX5MAPK1
Cinnamaldehyde SCHEMBL29210909 0.81 LMNA (0.62) ALDH1A1LMNATRPA1ALOX5MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3471691-A1 MIXTURE COMPRISING AT LEAST DIHYDRO-5-PENTYL-2(3H)-FURANONE AND 2,4-DIMETHYL-4-PHENYLTETRAHYDROFURAN AND USE THEREOF FOR MASKING UNPLEASANT ODOURS Expressions Parfumees (FR) 2019-04-24 EP disclosed