Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamaldehyde SCHEMBL28716525 | 0.83 | ALDH1A1 (0.62) | LMNAALDH1A1TRPA1ALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL29210909 | 0.83 | LMNA (0.62) | LMNAALDH1A1TRPA1ALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL28716524 | 0.83 | ALDH1A1 (0.62) | LMNAALDH1A1TRPA1ALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL28633503 | 0.82 | ALDH1A1 (0.67) | LMNAALDH1A1TRPA1ALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL28633504 | 0.82 | ALDH1A1 (0.67) | LMNAALDH1A1TRPA1ALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL8420413 | 0.82 | ALDH1A1 (0.72) | LMNAALDH1A1TRPA1ALOX5MAPK1 | |
| Benzaldehyde SCHEMBL1169911 | 0.82 | ALDH1A1 (0.56) | LMNAALDH1A1HDAC3EGFRSIGMAR1 | |
| (Z)-1,2-Diphenylethene SCHEMBL5489824 | 0.82 | SIGMAR1 (0.61) | LMNAALDH1A1HDAC3EGFRSIGMAR1 | |
| Cinnamaldehyde SCHEMBL20912968 | 0.81 | ALDH1A1 (0.60) | LMNAALDH1A1TRPA1ALOX5MAPK1 | |
| Cinnamaldehyde SCHEMBL20912967 | 0.81 | ALDH1A1 (0.60) | LMNAALDH1A1TRPA1ALOX5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078542-B2 | Nonlinear optical compounds and methods for their preparation | UNIVERSITY OF WASHINGTON (US) | 2006-07-18 | — | — | US | disclosed |
| US-7014796-B2 | Nonlinear optical compounds and methods for their preparation | UNIVERSITY OF WASHINGTON (US) | 2006-03-21 | — | — | US | disclosed |
| US-20050023507-A1 | pi-electron donor group bonded to a pi-electron conjugated bridge group bonded to a mono- or dicyanodihydrofuran acceptor; large hyperpolarizability, dipole moment, and electrooptic coefficients; electrooptics | UNIVERSITY OF WASHINGTON (US) | 2005-02-03 | — | — | US | disclosed |
| WO-2004065384-A1 | NONLINEAR OPTICAL COMPOUNDS AND METHODS FOR THEIR PREPARATION | UNIVERSITY OF WASHINGTON (US) | 2004-08-05 | — | — | WO | disclosed |
| US-20040135130-A1 | Nonlinear optical compounds and methods for their preparation | UNIVERSITY OF WASHINGTON | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050023507-A1 | pi-electron donor group bonded to a pi-electron conjugated bridge group bonded to a mono- or dicyanodihydrofuran acceptor; large hyperpolarizability, dipole moment, and electrooptic coefficients; electrooptics | PCNA, ETFA, POF1B | LMNA 1276/4885ALDH1A1 2191/4885TRPA1 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.