SCHEMBL20915486

SCHEMBL20915486

CC(=O)OC(C)Cc1c2ccccc2c(CC(C)OC(C)=O)c2c(Oc3c(C)ccc4c(CC(C)OC(C)=O)c5ccccc5c(CC(C)OC(C)=O)c34)c(C)ccc12

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HSD17B10 Q99714 1/20 0.33
RAD52 P43351 1/20 0.32
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20915287 0.86 ESRRA (0.30)
SCHEMBL20915633 0.86
SCHEMBL20915342 0.83 KDM4E (0.37) HTTKDM4EGAAMAPTHSD17B10
SCHEMBL20915441 0.82 TUBB4A (0.33) HTTMAPT
SCHEMBL20915552 0.81 GAA (0.33) HTTKDM4EGAAMAPTHSD17B10
SCHEMBL20915362 0.81 L3MBTL1 (0.34) KDM4EGAAMAPTHSD17B10RAD52
SCHEMBL20915429 0.74 RAD52 (0.56) HTTKDM4ETP53GAAMAPT
SCHEMBL20915635 0.73 RAD52 (0.52) HTTKDM4ETP53GAAMAPT
SCHEMBL20915474 0.73
SCHEMBL20915583 0.70 CYP1A2 (0.35) HTTKDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11149103-B2 Photopolymerization sensitizer composition and photopolymerizable composition comprising the same KAWASAKI KASEI CHEMICALS LTD. (JP) 2021-10-19 US disclosed
US-20190119426-A1 PHOTOPOLYMERIZATION SENSITIZER COMPOSITION AND PHOTOPOLYMERIZABLE COMPOSITION COMPRISING THE SAME KAWASAKI KASEI CHEMICALS LTD. (JP) 2019-04-25 US disclosed