SCHEMBL20915342

SCHEMBL20915342

CC(=O)OC(C)Cc1c2ccccc2c(CC(C)OC(C)=O)c2c(Oc3c(Oc4ccccc4)ccc4c(CC(C)OC(C)=O)c5ccccc5c(CC(C)OC(C)=O)c34)c(Oc3ccccc3)ccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.37
LMNA P02545 3/20 0.37
POLB P06746 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
MAPT P10636 2/20 0.37
HTT P42858 1/20 0.37
RECQL P46063 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
MPI P34949 1/20 0.34
TSPO P30536 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
SCN9A Q15858 1/20 0.32
TTR P02766 1/20 0.32
ACACB O00763 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20915674 0.87 THRB (0.33) KDM4ELMNAPOLBSMN1; SMN2L3MBTL1
SCHEMBL20915486 0.83 HTT (0.33) KDM4EMAPTHTTGAAHSD17B10
SCHEMBL20915529 0.83 LMNA (0.36) KDM4ELMNAPOLBSMN1; SMN2L3MBTL1
SCHEMBL20915287 0.82 ESRRA (0.30) ESRRA
SCHEMBL20915441 0.80 TUBB4A (0.33) L3MBTL1MAPTHTTALDH1A1HPGD
SCHEMBL20915362 0.79 L3MBTL1 (0.34) KDM4EPOLBSMN1; SMN2L3MBTL1MAPT
SCHEMBL20915625 0.77 RAD52 (0.49) KDM4ELMNAPOLBSMN1; SMN2L3MBTL1
SCHEMBL20915520 0.75 RAD52 (0.47) KDM4ELMNAPOLBSMN1; SMN2L3MBTL1
SCHEMBL20915437 0.73 LTA4H (0.39) KDM4ELMNAPOLBSMN1; SMN2L3MBTL1
SCHEMBL20915392 0.71 KDM4E (0.41) KDM4ELMNAPOLBSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11149103-B2 Photopolymerization sensitizer composition and photopolymerizable composition comprising the same KAWASAKI KASEI CHEMICALS LTD. (JP) 2021-10-19 US disclosed
US-20190119426-A1 PHOTOPOLYMERIZATION SENSITIZER COMPOSITION AND PHOTOPOLYMERIZABLE COMPOSITION COMPRISING THE SAME KAWASAKI KASEI CHEMICALS LTD. (JP) 2019-04-25 US disclosed