Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20480768 | 0.85 | MAPT (0.49) | ALDH1A1MAPTGAALMNAALOX15 | |
| SCHEMBL5221465 | 0.83 | PDPK1 (0.54) | ALDH1A1MAPTGAALMNAALOX15 | |
| SCHEMBL2091031 | 0.81 | TDP1 (0.56) | ALDH1A1MAPTGAALMNAMAPK1 | |
| SCHEMBL20480769 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTGAALMNAALOX15 | |
| SCHEMBL28272959 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTGAALMNAALOX15 | |
| SCHEMBL5973543 | 0.79 | ALDH1A1 (0.61) | ALDH1A1MAPTGAALMNAALOX15 | |
| SCHEMBL805050 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MAPTGAALMNAALOX15 | |
| SCHEMBL5872790 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MAPTGAALMNAALOX15 | |
| SCHEMBL14127136 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPTGAALMNAALOX15 | |
| SCHEMBL77032 | 0.74 | KMT2A (0.68) | ALDH1A1MAPTGAAALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104292224-A | Benzothiazole amide derivatives containing substituted 1,3,4-thiadiazole (oxadiazole) thioether as well as preparation method and application of derivatives | UNIV GUIZHOU | 2015-01-21 | — | — | CN | claimed |
| US-8163761-B2 | Methods and compositions for treating disorders | HYDRA BIOSCIENCES, INC. (US) | 2012-04-24 | — | — | US | disclosed |