SCHEMBL20918261

SCHEMBL20918261

[c]1[c]c2c(cc1-c1ccccc1)-c1ccccc1C2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 2/20 0.37
NPC1 O15118 2/20 0.37
MAPT P10636 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
SRD5A2 P31213 1/20 0.37
CYP1A2 P05177 3/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2C19 P33261 1/20 0.36
MAOA P21397 3/20 0.34
KDR P35968 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
BCHE P06276 1/20 0.32
CES1 P23141 1/20 0.32
PNMT P11086 1/20 0.31
PKM P14618 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20918382 0.80 ALDH1A1 (0.35) ALDH1A1KDM4ENPC1MAPTRAB9A
SCHEMBL216860 0.74 ALDH1A1 (0.38) ALDH1A1KDM4ENPC1MAPTRAB9A
SCHEMBL2051734 0.72 CYP1A2 (0.38) ALDH1A1KDM4ENPC1MAPTRAB9A
SCHEMBL1539776 0.71 ALDH1A1 (0.36) ALDH1A1KDM4ENPC1MAPTRAB9A
SCHEMBL23087114 0.70 KDR (0.39) ALDH1A1KDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL473154 0.70 MAOA (0.56) ALDH1A1KDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL27273010 0.68 MAOA (0.54) ALDH1A1KDM4ENPC1MAPTRAB9A
SCHEMBL6003336 0.68 KDR (0.36) MAOAKDRADORA2AADORA1BCHE
Fluorene SCHEMBL9079589 0.67 ALDH1A1 (0.50) ALDH1A1KDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL14118022 0.67 MAOA (0.65) ALDH1A1KDM4ENPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019078443-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed