SCHEMBL216860

SCHEMBL216860

[c]1c(-c2ccccc2)ccc2c1Cc1ccccc1-2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SRD5A2 P31213 2/20 0.38
MAOA P21397 3/20 0.35
KDR P35968 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
CYP1A2 P05177 3/20 0.34
CYP3A4 P08684 2/20 0.34
CYP2C19 P33261 1/20 0.34
BCHE P06276 1/20 0.33
CES1 P23141 1/20 0.33
PNMT P11086 1/20 0.32
ADRA2A P08913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717055 0.85 TDP2 (0.46) NPC1LMNAMAPTRAB9ASMN1; SMN2
SCHEMBL3443207 0.83 ADORA2A (0.38) ALDH1A1KDM4ENPC1LMNAMAPT
SCHEMBL6571163 0.83 MEN1 (0.38) ALDH1A1KDM4ENPC1LMNAMAPT
SCHEMBL313500 0.79 PNMT (0.44) ALDH1A1KDM4ENPC1LMNAMAPT
SCHEMBL2965677 0.79 ALDH1A1 (0.36) ALDH1A1KDM4ENPC1LMNAMAPT
SCHEMBL2974521 0.79 KDM4E (0.36) ALDH1A1KDM4ENPC1LMNAMAPT
SCHEMBL217877 0.79 ALDH1A1 (0.36) ALDH1A1KDM4ENPC1LMNAMAPT
SCHEMBL2974781 0.78 KDM4E (0.35) ALDH1A1KDM4ENPC1LMNAMAPT
SCHEMBL1029595 0.77 KDM4E (0.34) ALDH1A1KDM4ENPC1LMNAMAPT
SCHEMBL2972402 0.76 KDM4E (0.33) ALDH1A1KDM4ENPC1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1440 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115403580-B Nitrogen-containing heterocyclic compound and application thereof 宁波卢米蓝新材料有限公司 2024-04-30 CN claimed
US-20240083876-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-03-14 US claimed
CN-117417261-A 2, 3-substituted naphthylamine derivative organic light-emitting compound and organic electroluminescent device CMDL有限公司 2024-01-19 CN claimed
CN-114516803-B Fused ring compound and application thereof 宁波卢米蓝新材料有限公司 2024-01-09 CN claimed
CN-117304207-A Compound containing phenoxazinooxazole structure and application thereof 烟台九目化学股份有限公司 2023-12-29 CN claimed
CN-117247324-A Fused ring compound and application thereof 宁波卢米蓝新材料有限公司 2023-12-19 CN claimed
CN-117143058-A Triarylamine compound and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2023-12-01 CN claimed
CN-116724020-A Novel compound and organic light emitting device comprising the same 株式会社LG化学 2023-09-08 CN claimed
CN-116655663-A Boron-containing organic compound and organic electroluminescent device prepared from same 江苏三月科技股份有限公司 2023-08-29 CN claimed
WO-2023085670-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-05-19 WO claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-6921799-B1 Olefin polymerization process BOREALIS A/S (DK) 2005-07-26 US claimed
CN-1157427-C Polymerization method for olefrines �����ɷ� 2004-07-14 CN claimed
EP-0993478-B1 OLEFIN POLYMERIZATION PROCESS BOREALIS TECH OY (FI) 2004-04-07 EP claimed
US-6245938-B1 COMPOUND SUITABLE FOR USE BOTH AS DERIVATIZING GROUP FOR OPTICAL SEPARATION OF ENANTIOMERS AND AS PROTECTING GROUP FOR PREPARATION OF MISACYLATED TRNA UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2001-06-12 US claimed
CN-1260807-A Polymerization method for olefrines BOREALL AS (DK) 2000-07-19 CN claimed
EP-0993478-A1 OLEFIN POLYMERIZATION PROCESS BOREALIS A/S (DK) 2000-04-19 EP claimed
WO-1998058001-A1 OLEFIN POLYMERIZATION PROCESS COCKBAIN, JULIAN (GB) 1998-12-23 WO claimed
EP-0694041-A1 A PROCESS AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS CONTAINING N-ALPHA-METHYLARGININE THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-01-31 EP claimed
WO-1994022911-A2 A PROCESS AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS CONTAINING Nα-METHYLARGININE THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-10-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240083876-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SOD1, TERT, AOC2 ALDH1A1 572/4885KDM4E 868/4885NPC1 3149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.