SCHEMBL20920147

SCHEMBL20920147

CC(OC([O])=O)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.47
NPC1 O15118 2/20 0.47
HTR2B P41595 3/20 0.41
HTR7 P34969 2/20 0.41
PNMT P11086 1/20 0.39
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SRD5A2 P31213 1/20 0.35
HTR2C P28335 2/20 0.35
MAOA P21397 2/20 0.35
CYP1A2 P05177 1/20 0.35
ADRA2A P08913 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
MAPK1 P28482 1/20 0.34
DRD2 P14416 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2233833 0.87 RAB9A (0.46) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL4462321 0.81 NPC1 (0.41) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL1567119 0.81 NPC1 (0.50) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL9449677 0.80 PNMT (0.44) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL2316415 0.79 RAB9A (0.42) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL9420910 0.78 NPC1 (0.50) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL30710206 0.77 NPC1 (0.40) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL1567105 0.77 RAB9A (0.50) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL2231457 0.77 NPC1 (0.47) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL1567173 0.77 NPC1 (0.47) RAB9ANPC1HTR2BHTR7PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019078171-A1 METHOD FOR CONCENTRATING OR SEPARATING POLYMER COMPOUND 国立大学法人京都大学 2019-04-25 WO disclosed