SCHEMBL9449677

SCHEMBL9449677

COC(C)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.44
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HTR7 P34969 1/20 0.36
HTR2B P41595 1/20 0.36
EGFR P00533 1/20 0.36
PGR P06401 1/20 0.35
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GRM5 P41594 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28514359 0.86 PNMT (0.39) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL2316415 0.83 RAB9A (0.42) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL28860706 0.83 PNMT (0.37) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL6675580 0.82 PNMT (0.49) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL6672847 0.82 PNMT (0.49) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL29617348 0.82 PNMT (0.49) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL4462321 0.81 NPC1 (0.41) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL6557930 0.81 PNMT (0.47) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL20920147 0.80 RAB9A (0.47) PNMTNPC1RAB9AALDH1A1KDM4E
SCHEMBL7597399 0.80 PNMT (0.41) PNMTNPC1RAB9AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1473809-A Diethers suitable for use in the preparation of ziegler-natta catalysts ��������ϩ����������޹�˾ 2004-02-11 CN claimed
CN-1141285-A Diethers suitable for use in the preparation of ziegler-natta catalysts MONTELL NORTH AMERICA INC (US) 1997-01-29 CN claimed
CN-106543310-A A kind of olefin polymerization catalyst system and its application 中国石油化工股份有限公司 2017-03-29 CN disclosed
CN-103626894-B For catalyst component and the method for preparing catalyst thereof of olefinic polyreaction SINOPEC CORP. (CN) 2016-03-30 CN disclosed
CN-103626895-B For catalyst component and the method for preparing catalyst thereof of olefinic polyreaction SINOPEC CORP. (CN) 2016-03-30 CN disclosed
CN-103626893-B For catalyst component and the method for preparing catalyst thereof of olefinic polyreaction SINOPEC CORP. (CN) 2016-03-30 CN disclosed
CN-103626896-B For catalyst component and the method for preparing catalyst thereof of olefinic polyreaction SINOPEC CORP. (CN) 2016-03-30 CN disclosed
CN-103626893-A Catalyst component for alkene polymerization reactions and preparation method of catalyst prepared from the catalyst component CHINA PETROLEUM & CHEMICAL 2014-03-12 CN disclosed
CN-103626894-A Catalyst component for alkene polymerization reaction and preparation method of catalyst thereof CHINA PETROLEUM & CHEMICAL 2014-03-12 CN disclosed
CN-103626895-A Catalyst component for alkene polymerization reactions and preparation method of catalyst thereof CHINA PETROLEUM & CHEMICAL 2014-03-12 CN disclosed
CN-1289451-C Diethers suitable for use in the preparation of ziegler-natta catalysts BASEL POLELEFINE ITALY S P A (IT) 2006-12-13 CN disclosed
CN-1210243-C Synthesis method of diether BASEL NORTH AMERICA CO LTD (US) 2005-07-13 CN disclosed
CN-1491929-A Diethers suitable for use in the preparation of ziegler-natta catalysts 2004-04-28 CN disclosed
CN-1473809-A Diethers suitable for use in the preparation of ziegler-natta catalysts ��������ϩ����������޹�˾ 2004-02-11 CN disclosed
CN-1121368-C Diethers suitable for use in the preparation of ziegler-natta catalysts MONTELL NORTH AMERICA INC (US) 2003-09-17 CN disclosed
CN-1141285-A Diethers suitable for use in the preparation of ziegler-natta catalysts MONTELL NORTH AMERICA INC (US) 1997-01-29 CN disclosed
EP-0531443-A4 METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN 1993-04-21 EP disclosed
EP-0531443-A1 METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN NOVA PHARMACEUTICAL CORPORATION (US) 1993-03-17 EP disclosed