Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 3/20 | 0.55 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.55 |
| ▸ | MATK | P42679 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.55 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.50 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.50 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | FLT4 | P35916 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.46 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2094065 | 0.92 | PIM3 (0.66) | PIM3MAPKAPK3RPS6KB1MATKDYRK1A | |
| SCHEMBL2093254 | 0.92 | PIM3 (0.66) | PIM3MAPKAPK3RPS6KB1MATKDYRK1A | |
| SCHEMBL2094055 | 0.92 | PIM3 (0.66) | PIM3MAPKAPK3RPS6KB1MATKDYRK1A | |
| Hydrochloric Acid SCHEMBL2093820 | 0.91 | PIM3 (0.65) | PIM3MAPKAPK3RPS6KB1MATKDYRK1A | |
| SCHEMBL2092727 | 0.90 | PIM3 (0.52) | PIM3MAPKAPK3RPS6KB1MATKDYRK1A | |
| SCHEMBL2092702 | 0.89 | PIM3 (0.57) | PIM3MAPKAPK3RPS6KB1MATKDYRK1A | |
| SCHEMBL2092654 | 0.88 | PIM3 (0.63) | PIM3MAPKAPK3RPS6KB1MATKDYRK1A | |
| SCHEMBL2093744 | 0.85 | PIM3 (0.45) | PIM3MAPKAPK3RPS6KB1MATKDYRK1A | |
| SCHEMBL2097125 | 0.85 | LMNA (0.48) | PIM3MAPKAPK3RPS6KB1MATKDYRK1A | |
| SCHEMBL2094951 | 0.85 | LMNA (0.48) | PIM3MAPKAPK3RPS6KB1MATKDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232818-A1 | Antibacterial compounds | ABBVIE INC. | 2003-12-18 | — | — | US | claimed |
| US-8163769-B2 | 1,8-naphthyridine derivatives | ABBOTT LABORATORIES (US) | 2012-04-24 | — | — | US | disclosed |
| US-20030232818-A1 | Antibacterial compounds | ABBVIE INC. | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232818-A1 | Antibacterial compounds | PGLS, UGT1A1, CASP1 | PIM3 3424/4885MAPKAPK3 2241/4885RPS6KB1 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.