SCHEMBL2092290

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Difucol Hexamethyl Ether SCHEMBL505203	0.65	CYP1A2 (0.60)	LMNASMN1; SMN2ALDH1A1CYP1A2CYP3A4
	SCHEMBL2092500	0.65	ALDH1A1 (0.44)	LMNAHPGDALDH1A1CYP1A2CYP3A4
	SCHEMBL1047857	0.65	ALDH1A1 (0.46)	SMN1; SMN2ALDH1A1CYP1A2CYP3A4CA1
	SCHEMBL656828	0.61	ALDH1A1 (0.61)	LMNATSHRMEN1KMT2AHPGD
	SCHEMBL8868853	0.61	RAB9A (0.45)	TSHRMEN1HTTKMT2AHPGD
	SCHEMBL4865554	0.61	NOTUM (0.68)	LMNAHTTHPGDSMN1; SMN2ALDH1A1
	SCHEMBL29159184	0.61	ALDH1A1 (0.43)	LMNAHTTSMN1; SMN2ALDH1A1CYP1A2
	SCHEMBL17684661	0.61	ALDH1A1 (0.61)	LMNAHPGDSMN1; SMN2ALDH1A1CYP1A2
	SCHEMBL13049389	0.61	NPC1 (0.61)	TSHRMEN1KMT2AHPGDSMN1; SMN2
	SCHEMBL658771	0.61	RPS6KB1 (0.47)	LMNAHTTHPGDSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.