Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924019 | 0.96 | XDH (0.39) | METAP2XDHTSHRHRH1HTR6 | |
| SCHEMBL20923117 | 0.95 | METAP2 (0.37) | METAP2XDHTSHRHRH1HTR6 | |
| SCHEMBL20923114 | 0.91 | METAP2 (0.40) | METAP2XDHTSHRKDM4EPDE5A | |
| SCHEMBL19919548 | 0.91 | METAP2 (0.40) | METAP2XDHTSHRHRH1HTR6 | |
| SCHEMBL20924018 | 0.91 | METAP2 (0.37) | METAP2XDHTSHRHRH1HTR6 | |
| SCHEMBL20923257 | 0.90 | METAP2 (0.36) | METAP2XDHTSHRKDM4EPDE5A | |
| SCHEMBL20923636 | 0.89 | KIF11 (0.41) | METAP2XDHTSHRKDM4EPDE5A | |
| SCHEMBL20924017 | 0.87 | METAP2 (0.40) | METAP2XDHTSHRKDM4EPDE5A | |
| SCHEMBL20924059 | 0.86 | MAPK14 (0.38) | METAP2XDHTSHRKDM4EPDE5A | |
| SCHEMBL20923121 | 0.86 | CYP19A1 (0.38) | METAP2XDHHRH1HTR6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266772-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |