SCHEMBL19909006

SCHEMBL19909006

N#Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(C#N)c(-c3ccncc3)cc2-n2c3ccccc3c3cc(-c4ccc(C#N)cc4C#N)ccc32)c(C#N)c1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.38
CYP11B1 P15538 3/20 0.38
CYP11B2 P19099 3/20 0.38
CYP19A1 P11511 1/20 0.38
PTGER4 P35408 1/20 0.37
FLT3 P36888 2/20 0.36
XDH P47989 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.34
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
LRRK2 Q5S007 2/20 0.33
SQOR Q9Y6N5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19919765 0.95 STS (0.38) STSCYP11B1CYP11B2CYP19A1PTGER4
SCHEMBL19919622 0.95 STS (0.39) STSCYP11B1CYP11B2CYP19A1FLT3
SCHEMBL19909005 0.94 STS (0.38) STSCYP11B1CYP11B2CYP19A1FLT3
SCHEMBL20923142 0.93 CYP19A1 (0.38) STSCYP11B1CYP11B2CYP19A1PTGER4
SCHEMBL19913203 0.92 CYP19A1 (0.38) CYP11B1CYP11B2CYP19A1PTGER4FLT3
SCHEMBL20923143 0.92 PTGER4 (0.37) STSCYP11B1CYP11B2CYP19A1PTGER4
SCHEMBL20923836 0.92 CYP11B1 (0.39) STSCYP11B1CYP11B2CYP19A1PTGER4
SCHEMBL19909032 0.92 PTGER4 (0.38) CYP11B1CYP11B2CYP19A1PTGER4FLT3
SCHEMBL19909030 0.90 TRPA1 (0.41) CYP11B1CYP11B2CYP19A1SQOR
SCHEMBL19909300 0.90 STS (0.38) STSCYP11B1CYP11B2CYP19A1FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 STS 2528/4885CYP11B1 610/4885CYP11B2 402/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 STS 2306/4885CYP11B1 1400/4885CYP11B2 965/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 STS 2528/4885CYP11B1 610/4885CYP11B2 402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.