Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 6/20 | 0.46 |
| ▸ | METTL3 | Q86U44 | 8/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20419234 | 0.84 | ADK (0.59) | ADKMETTL3 | |
| SCHEMBL20419136 | 0.84 | ADK (0.59) | ADKMETTL3 | |
| SCHEMBL20938262 | 0.84 | ADK (0.59) | ADKMETTL3 | |
| SCHEMBL22912609 | 0.83 | ADK (0.43) | ADKMETTL3SLC29A1 | |
| SCHEMBL20917266 | 0.83 | ADK (0.51) | ADKMETTL3SLC29A1 | |
| SCHEMBL20917264 | 0.77 | SLC29A1 (0.39) | ADKMETTL3SLC29A1 | |
| SCHEMBL22912613 | 0.77 | SLC29A1 (0.39) | ADKMETTL3SLC29A1 | |
| SCHEMBL20938192 | 0.75 | ALDH1A1 (0.43) | ADKMETTL3SLC29A1 | |
| SCHEMBL14305600 | 0.74 | ADK (0.60) | ADKMETTL3 | |
| SCHEMBL13952411 | 0.74 | ADK (0.60) | ADKMETTL3SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3697800-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | Universiteit Gent (BE) | 2020-08-26 | — | — | EP | disclosed |
| WO-2019076633-A1 | NUCLEOSIDE ANALOGUES FOR THE TREATMENT OF PARASITIC INFECTIONS | UNIVERSITEIT GENT (BE) | 2019-04-25 | — | — | WO | disclosed |