Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | MAT2A | P31153 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20923699 | 0.95 | ALOX5AP (0.40) | KIF11CYP19A1CYP11B1CYP11B2ALOX5AP | |
| SCHEMBL20924005 | 0.92 | KIF11 (0.41) | KIF11CYP19A1CYP11B1CYP11B2METAP2 | |
| SCHEMBL20923674 | 0.92 | ALOX5AP (0.38) | KIF11CYP19A1CYP11B1CYP11B2ALOX5AP | |
| SCHEMBL20924087 | 0.90 | METAP2 (0.35) | CYP19A1CYP11B1CYP11B2ALOX5APFEN1 | |
| SCHEMBL20923307 | 0.89 | LMNA (0.39) | CYP19A1CYP11B1CYP11B2METAP2XDH | |
| SCHEMBL20923305 | 0.89 | LMNA (0.39) | CYP19A1CYP11B1CYP11B2METAP2XDH | |
| SCHEMBL20923309 | 0.88 | ALOX5AP (0.40) | KIF11CYP19A1CYP11B1CYP11B2ALOX5AP | |
| SCHEMBL20923573 | 0.88 | ALOX5AP (0.38) | CYP19A1CYP11B1CYP11B2ALOX5APFEN1 | |
| SCHEMBL19913204 | 0.86 | KIF11 (0.41) | KIF11CYP19A1CYP11B1CYP11B2ALOX5AP | |
| SCHEMBL20924034 | 0.86 | METAP2 (0.40) | KIF11CYP19A1CYP11B1CYP11B2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266772-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |