Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837458 | 0.84 | KDM1A (0.70) | KDM1AMEN1POLBKMT2ACTSS | |
| SCHEMBL15136256 | 0.82 | KDM1A (1.00) | KDM1AMEN1POLBKMT2ACTSS | |
| SCHEMBL15137206 | 0.82 | KDM1A (1.00) | KDM1AMEN1POLBKMT2ACTSS | |
| SCHEMBL15135913 | 0.82 | KDM1A (1.00) | KDM1AMEN1POLBKMT2ACTSS | |
| Hydrochloric Acid SCHEMBL15136547 | 0.81 | KDM1A (0.97) | KDM1AMEN1POLBKMT2ACTSS | |
| Hydrochloric Acid SCHEMBL15136548 | 0.81 | KDM1A (0.97) | KDM1AMEN1POLBKMT2ACTSS | |
| SCHEMBL19865072 | 0.80 | KDM1A (0.62) | KDM1ACTSSALDH1A1KDM4ECYP1A2 | |
| SCHEMBL6837460 | 0.79 | KDM1A (0.54) | KDM1AMEN1POLBKMT2ACTSS | |
| SCHEMBL6837433 | 0.79 | KDM1A (0.49) | KDM1AMEN1POLBKMT2ACTSS | |
| SCHEMBL28325847 | 0.79 | KDM1A (0.57) | KDM1AMEN1POLBKMT2ACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |