Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837433 | 0.88 | KDM1A (0.49) | KDM1ACTSSMEN1KMT2APOLB | |
| SCHEMBL528169 | 0.85 | KDM1A (0.73) | KDM1ACTSSKDM4EALDH1A1VCP | |
| SCHEMBL15136574 | 0.85 | KDM1A (0.73) | KDM1ACTSSKDM4EALDH1A1VCP | |
| SCHEMBL528168 | 0.85 | KDM1A (0.73) | KDM1ACTSSKDM4EALDH1A1VCP | |
| Hydrochloric Acid SCHEMBL527621 | 0.84 | KDM1A (0.71) | KDM1ACTSSKDM4EALDH1A1VCP | |
| Hydrochloric Acid SCHEMBL527622 | 0.84 | KDM1A (0.71) | KDM1ACTSSKDM4EALDH1A1VCP | |
| SCHEMBL6837458 | 0.83 | KDM1A (0.70) | KDM1ACTSSMEN1KMT2APOLB | |
| SCHEMBL20923959 | 0.79 | KDM1A (0.70) | KDM1ACTSSMEN1KMT2APOLB | |
| SCHEMBL15135874 | 0.78 | KDM1A (0.49) | KDM1AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL528925 | 0.78 | KDM1A (0.49) | KDM1AMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |
| WO-2012013727-A1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS S.A. (ES) | 2012-02-02 | — | — | WO | disclosed |