Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20923959 | 0.84 | KDM1A (0.70) | KDM1AKDM4EALDH1A1MAOBCTSS | |
| SCHEMBL6837460 | 0.83 | KDM1A (0.54) | KDM1AKDM4EALDH1A1MAOBCTSS | |
| SCHEMBL15136658 | 0.83 | KDM1A (1.00) | KDM1AKDM4EALDH1A1MAOBCTSS | |
| SCHEMBL527537 | 0.83 | KDM1A (1.00) | KDM1AKDM4EALDH1A1MAOBCTSS | |
| SCHEMBL527536 | 0.83 | KDM1A (1.00) | KDM1AKDM4EALDH1A1MAOBCTSS | |
| Hydrochloric Acid SCHEMBL526904 | 0.82 | KDM1A (0.97) | KDM1AKDM4EALDH1A1MAOBCTSS | |
| Hydrochloric Acid SCHEMBL526903 | 0.82 | KDM1A (0.97) | KDM1AKDM4EALDH1A1MAOBCTSS | |
| SCHEMBL6837433 | 0.78 | KDM1A (0.49) | KDM1AKDM4EALDH1A1MAOBCTSS | |
| SCHEMBL527392 | 0.78 | KDM1A (0.69) | KDM1AKDM4EALDH1A1MAOBCTSS | |
| SCHEMBL529514 | 0.78 | KDM1A (0.69) | KDM1AKDM4EALDH1A1MAOBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |
| WO-2012013727-A1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS S.A. (ES) | 2012-02-02 | — | — | WO | disclosed |