Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.40 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837460 | 0.88 | KDM1A (0.54) | KDM1ACTSSMEN1KMT2APOLB | |
| SCHEMBL15137127 | 0.85 | KDM1A (0.67) | KDM1ACTSSKMOKDM4EALDH1A1 | |
| SCHEMBL527208 | 0.85 | KDM1A (0.67) | KDM1ACTSSKMOKDM4EALDH1A1 | |
| SCHEMBL527207 | 0.85 | KDM1A (0.67) | KDM1ACTSSKMOKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL527561 | 0.84 | KDM1A (0.66) | KDM1ACTSSKMOKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL527560 | 0.84 | KDM1A (0.66) | KDM1ACTSSKMOKDM4EALDH1A1 | |
| SCHEMBL20923959 | 0.79 | KDM1A (0.70) | KDM1ACTSSMEN1KMT2APOLB | |
| SCHEMBL6837458 | 0.78 | KDM1A (0.70) | KDM1ACTSSMEN1KMT2APOLB | |
| SCHEMBL15136574 | 0.73 | KDM1A (0.73) | KDM1ACTSSKDM4EALDH1A1MAOB | |
| SCHEMBL528168 | 0.73 | KDM1A (0.73) | KDM1ACTSSKDM4EALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |
| WO-2012013727-A1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS S.A. (ES) | 2012-02-02 | — | — | WO | disclosed |