Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924030 | 0.97 | PDE10A (0.37) | HPGDKDM4ELMNACYP2C19PDE5A | |
| SCHEMBL20924131 | 0.96 | TRPA1 (0.40) | HPGDKDM4ELMNACYP2C19PDE5A | |
| SCHEMBL20923189 | 0.94 | AR (0.41) | HPGDKDM4ELMNACYP2C19PDE5A | |
| SCHEMBL20923723 | 0.93 | TRPA1 (0.38) | HPGDKDM4ELMNACYP2C19PDE5A | |
| SCHEMBL20923149 | 0.91 | CYP1A2 (0.39) | HPGDKDM4ELMNACYP2C19PDE5A | |
| SCHEMBL19919602 | 0.91 | TRPA1 (0.43) | HPGDKDM4ELMNACYP2C19PDE5A | |
| SCHEMBL20923148 | 0.91 | CYP1A2 (0.38) | HPGDKDM4ELMNACYP2C19PDE5A | |
| SCHEMBL20923191 | 0.91 | AR (0.39) | HPGDKDM4ELMNACYP2C19PDE5A | |
| SCHEMBL20924125 | 0.89 | AR (0.41) | HPGDKDM4ELMNACYP2C19PDE5A | |
| SCHEMBL20924100 | 0.88 | CYP11B1 (0.40) | HPGDKDM4ELMNACYP2C19PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266772-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |