Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 2/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.45 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.45 |
| ▸ | SUV39H2 | Q9H5I1 | 17/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | MATK | P42679 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093107 | 1.00 | PIM3 (0.45) | PIM3DYRK3SRPK1CSNK1G1SUV39H2 | |
| SCHEMBL2092722 | 1.00 | PIM3 (0.45) | PIM3DYRK3SRPK1CSNK1G1SUV39H2 | |
| SCHEMBL2093422 | 0.94 | SUV39H2 (0.41) | PIM3DYRK3SRPK1CSNK1G1SUV39H2 | |
| SCHEMBL2097591 | 0.93 | SUV39H2 (0.41) | PIM3DYRK3SRPK1CSNK1G1SUV39H2 | |
| SCHEMBL2091583 | 0.93 | SUV39H2 (0.40) | PIM3DYRK3SRPK1CSNK1G1SUV39H2 | |
| SCHEMBL2093143 | 0.93 | SUV39H2 (0.40) | PIM3DYRK3SRPK1CSNK1G1SUV39H2 | |
| SCHEMBL2094630 | 0.93 | SUV39H2 (0.40) | PIM3DYRK3SRPK1CSNK1G1SUV39H2 | |
| SCHEMBL2094205 | 0.92 | SUV39H2 (0.40) | PIM3DYRK3SRPK1CSNK1G1SUV39H2 | |
| SCHEMBL2094393 | 0.90 | P2RX7 (0.35) | PIM3DYRK3SRPK1CSNK1G1RPS6KB1 | |
| SCHEMBL2094713 | 0.89 | LMNA (0.43) | SUV39H2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163769-B2 | 1,8-naphthyridine derivatives | ABBOTT LABORATORIES (US) | 2012-04-24 | — | — | US | disclosed |