SCHEMBL2094630

SCHEMBL2094630

CCOC(=O)c1cn(Cc2ccc(OC)cc2OC)c2nc(N3CC[C@@H](NC(=O)OC(C)(C)C)C3)c(F)c(C)c2c1=O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SUV39H2 Q9H5I1 16/20 0.40
GNRHR P30968 1/20 0.39
DYRK3 O43781 1/20 0.39
PIM3 Q86V86 1/20 0.39
SRPK1 Q96SB4 1/20 0.39
CSNK1G1 Q9HCP0 1/20 0.39
PDE10A Q9Y233 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2091583 1.00 SUV39H2 (0.40) SUV39H2GNRHRDYRK3PIM3SRPK1
SCHEMBL2093143 1.00 SUV39H2 (0.40) SUV39H2GNRHRDYRK3PIM3SRPK1
SCHEMBL2093638 0.94 SUV39H2 (0.40) SUV39H2GNRHRPDE10A
SCHEMBL2091986 0.94 SUV39H2 (0.39) SUV39H2GNRHRPDE10A
SCHEMBL2093107 0.93 PIM3 (0.45) SUV39H2DYRK3PIM3SRPK1CSNK1G1
SCHEMBL2092425 0.93 PIM3 (0.45) SUV39H2DYRK3PIM3SRPK1CSNK1G1
SCHEMBL2092722 0.93 PIM3 (0.45) SUV39H2DYRK3PIM3SRPK1CSNK1G1
SCHEMBL2093422 0.92 SUV39H2 (0.41) SUV39H2DYRK3PIM3SRPK1CSNK1G1
SCHEMBL2095546 0.90 GNRHR (0.40) GNRHR
SCHEMBL2093152 0.90 SUV39H2 (0.40) SUV39H2PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8163769-B2 1,8-naphthyridine derivatives ABBOTT LABORATORIES (US) 2012-04-24 US disclosed
US-20030232818-A1 Antibacterial compounds ABBVIE INC. 2003-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232818-A1 Antibacterial compounds PGLS, UGT1A1, CASP1 SUV39H2 4289/4885GNRHR 4352/4885DYRK3 4599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.