Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | MTOR | P42345 | 3/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | DDX3X | O00571 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19057796 | 0.74 | TGM2 (0.44) | NPC1ALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL23315095 | 0.72 | TGM2 (0.31) | — | |
| SCHEMBL21594549 | 0.72 | MAPT (0.46) | ALDH1A1GAARAB9ASMN1; SMN2POLB | |
| SCHEMBL25489239 | 0.71 | KDM4E (0.49) | NPC1ALDH1A1RAB9ASMN1; SMN2POLB | |
| SCHEMBL21392142 | 0.70 | NPSR1 (0.47) | NPSR1KCNQ3KCNQ2SORT1PIK3CA | |
| SCHEMBL20143351 | 0.68 | NPC1 (0.46) | NPSR1NPC1ALDH1A1GAARAB9A | |
| SCHEMBL2242286 | 0.68 | NPSR1 (0.57) | NPSR1KCNQ3KCNQ2SORT1NAMPT | |
| SCHEMBL30919458 | 0.68 | NPSR1 (0.57) | NPSR1KCNQ3KCNQ2SORT1NAMPT | |
| SCHEMBL23999852 | 0.67 | HDAC1 (0.46) | KCNQ3KCNQ2NPC1ALDH1A1RAB9A | |
| SCHEMBL13742463 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970260-B1 | IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS | PROXIMAGEN LLC (US) | 2019-04-24 | — | — | EP | disclosed |