Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25852263 | 0.80 | KMT2A (0.41) | HDAC1HDAC6RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13212217 | 0.76 | RAB9A (0.72) | HDAC1HDAC6KCNQ3KCNQ2RAB9A | |
| SCHEMBL4740817 | 0.74 | KCNQ3 (0.68) | HDAC1HDAC6KCNQ3KCNQ2RAB9A | |
| SCHEMBL6686328 | 0.73 | ALDH1A1 (0.71) | HDAC1HDAC6KCNQ3KCNQ2RAB9A | |
| SCHEMBL20261142 | 0.72 | HDAC1 (0.40) | HDAC1HDAC6RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22400083 | 0.71 | RAB9A (0.46) | HDAC1HDAC6KCNQ3KCNQ2RAB9A | |
| SCHEMBL4163710 | 0.70 | HDAC1 (0.54) | HDAC1HDAC6KCNQ3KCNQ2RAB9A | |
| SCHEMBL25761047 | 0.70 | DNMT1 (0.51) | HDAC1HDAC6MAPT | |
| SCHEMBL790699 | 0.67 | NAMPT (0.73) | RAB9ASMN1; SMN2TRPV1NPC1 | |
| SCHEMBL20924285 | 0.67 | NPSR1 (0.40) | HDAC1HDAC6KCNQ3KCNQ2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226519-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |