Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19057796 | 0.78 | TGM2 (0.44) | KDM4EALDH1A1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL18456642 | 0.77 | CA2 (0.42) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21594549 | 0.76 | MAPT (0.46) | ALDH1A1L3MBTL1SMN1; SMN2MAPK1HSD17B10 | |
| SCHEMBL23315095 | 0.76 | TGM2 (0.31) | — | |
| SCHEMBL21504863 | 0.76 | SMN1; SMN2 (0.46) | KDM4EALDH1A1L3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL6357758 | 0.73 | TGM2 (0.61) | KDM4EALDH1A1L3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL5422673 | 0.72 | ALDH1A1 (0.58) | KDM4EALDH1A1L3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL20924285 | 0.71 | NPSR1 (0.40) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL19403907 | 0.71 | SMN1; SMN2 (0.47) | KDM4EALDH1A1L3MBTL1SMN1; SMN2HSD17B10 | |
| SCHEMBL2906442 | 0.70 | SMN1; SMN2 (0.61) | KDM4EALDH1A1L3MBTL1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150953-A1 | SUBSTITUTED ISOPHTHALIC ACID DIAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150953-A1 | SUBSTITUTED ISOPHTHALIC ACID DIAMIDES | DDT, ZDHHC2, DDAH1 | KDM4E 3723/4885ALDH1A1 179/4885L3MBTL1 1376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.