Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 8/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16053697 | 0.84 | AOC3 (1.00) | AOC3KCNH2CYP1A2 | |
| SCHEMBL15353204 | 0.75 | AOC3 (0.56) | AOC3KCNH2HAO1ALDH1A1APP | |
| SCHEMBL23024879 | 0.72 | AOC3 (0.52) | AOC3KCNH2HAO1ALDH1A1HPGD | |
| SCHEMBL20924336 | 0.72 | AOC3 (0.52) | AOC3KCNH2KDM4EALDH1A1MDM2 | |
| SCHEMBL8308575 | 0.71 | PTGS2 (0.68) | HAO1PTGS2 | |
| SCHEMBL16053366 | 0.69 | AOC3 (0.75) | AOC3KCNH2 | |
| SCHEMBL13425022 | 0.67 | HAO1 (0.62) | AOC3KCNH2HAO1KDM4EALDH1A1 | |
| SCHEMBL5661209 | 0.66 | PTGS2 (0.61) | ALDH1A1APPPTGS2CYP1A2 | |
| SCHEMBL23505897 | 0.65 | AOC3 (0.42) | AOC3ALDH1A1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL4856109 | 0.65 | HAO1 (0.47) | AOC3KCNH2HAO1ALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970260-B1 | IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS | PROXIMAGEN LLC (US) | 2019-04-24 | — | — | EP | disclosed |