Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 10/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924334 | 0.72 | AOC3 (0.73) | AOC3MDM2KCNH2PIK3CDPIK3CA | |
| SCHEMBL20924456 | 0.70 | ALDH1A1 (0.34) | MDM2KCNH2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL16053697 | 0.69 | AOC3 (1.00) | AOC3KCNH2CYP1A2CYP3A4GAA | |
| SCHEMBL14463968 | 0.65 | — | — | |
| SCHEMBL20924339 | 0.62 | — | — | |
| SCHEMBL23505897 | 0.61 | AOC3 (0.42) | AOC3PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL24569275 | 0.60 | PIK3CD (0.38) | AOC3PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL4531549 | 0.59 | HIF1A (0.44) | AOC3GAAKDM4EALDH1A1 | |
| SCHEMBL20924531 | 0.59 | AOC3 (0.56) | AOC3KCNH2PIK3CAKDM4EALDH1A1 | |
| SCHEMBL22997255 | 0.58 | GABRA2 (0.37) | AOC3KCNH2GAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970260-B1 | IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS | PROXIMAGEN LLC (US) | 2019-04-24 | — | — | EP | disclosed |