Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867353 | 0.86 | HAO1 (0.59) | HAO1APPESR1ESR2ALDH1A1 | |
| SCHEMBL12123235 | 0.83 | KDM4E (0.44) | HAO1APPMAPK9MAPK10MAPK8 | |
| SCHEMBL14644422 | 0.82 | HAO1 (0.47) | HAO1APPESR1ESR2MAPK9 | |
| SCHEMBL13425022 | 0.82 | HAO1 (0.62) | HAO1APPESR1ESR2ALDH1A1 | |
| SCHEMBL14077257 | 0.82 | RELA (0.47) | HAO1APPMAPK9MAPK10MAPK8 | |
| SCHEMBL12980354 | 0.81 | HAO1 (0.56) | HAO1APPALDH1A1TSHRKMT2A | |
| SCHEMBL23733882 | 0.81 | HAO1 (0.45) | HAO1APPESR1ESR2ALDH1A1 | |
| SCHEMBL12123239 | 0.81 | KDM4E (0.42) | HAO1APPESR1ESR2MAPK9 | |
| SCHEMBL14644717 | 0.81 | HAO1 (0.46) | HAO1APPESR1ESR2MAPK9 | |
| SCHEMBL16356503 | 0.80 | HAO1 (0.46) | HAO1APPMAPK9MAPK10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130026458-A1 | CROSSLINKABLE COMPOSITION | DAICEL CORPORATION (JP) | 2013-01-31 | — | — | US | disclosed |
| US-20130026458-A1 | CROSSLINKABLE COMPOSITION | DAICEL CORPORATION (JP) | 2013-01-31 | — | — | US | disclosed |
| US-7388100-B2 | Tertiary amine compounds | NISHIO TETSUYA | 2008-06-17 | — | — | US | disclosed |
| US-7388100-B2 | Tertiary amine compounds | NISHIO TETSUYA | 2008-06-17 | — | — | US | disclosed |
| US-7388100-B2 | Tertiary amine compounds | NISHIO TETSUYA | 2008-06-17 | — | — | US | disclosed |
| US-20060145145-A1 | Tertiary amine compounds, organic semiconductor devices using the same and organic electroluminescence devices using the same | NISHIO TETSUYA | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060145145-A1 | Tertiary amine compounds, organic semiconductor devices using the same and organic electroluminescence devices using the same | PIEZO1, YES1, SAT1 | HAO1 1428/4885APP 3080/4885ESR1 1360/4885 |
| US-20130026458-A1 | CROSSLINKABLE COMPOSITION | DDC, ODC1, SRM | HAO1 2706/4885APP 538/4885ESR1 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.