SCHEMBL2092445

SCHEMBL2092445

CCCSC[C@H](NC(=O)CC[C@H](N)C(=O)O)C(=O)NCC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.64
GSTK1 Q9Y2Q3 1/20 0.64
GLO1 Q04760 3/20 0.60
NOD1 Q9Y239 10/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL800525 1.00 PTGS1 (0.64) PTGS1GSTK1GLO1NOD1
SCHEMBL3795790 0.93 PTGS1 (0.61) PTGS1GSTK1GLO1NOD1
SCHEMBL3795781 0.93 PTGS1 (0.61) PTGS1GSTK1GLO1NOD1
SCHEMBL2091663 0.92 PTGS1 (0.60) PTGS1GSTK1GLO1NOD1
SCHEMBL2091655 0.92 PTGS1 (0.60) PTGS1GSTK1GLO1NOD1
SCHEMBL7081151 0.91 PTGS1 (0.68) PTGS1GSTK1GLO1NOD1
SCHEMBL7081152 0.91 PTGS1 (0.68) PTGS1GSTK1GLO1NOD1
SCHEMBL17075566 0.91 PTGS1 (0.59) PTGS1GSTK1GLO1NOD1
SCHEMBL6926435 0.91 PTGS1 (0.59) PTGS1GSTK1GLO1NOD1
SCHEMBL2091563 0.91 PTGS1 (0.59) PTGS1GSTK1GLO1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3270889-B1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES MIRECA MEDICINES GMBH (DE) 2024-02-07 EP claimed
WO-2022074181-A1 NANOCARRIER FORMULATIONS FOR INHALATION EnhanX Biopharm Inc. (TW) 2022-04-14 WO claimed
EP-3395372-B1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM ENHANX BIOPHARM INC (TW) 2022-04-06 EP claimed
US-10322087-B2 Targeted liposomal delivery of cGMP analogues MIRECA MEDICINES GMBH (DE) 2019-06-18 US claimed
EP-2398500-B1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM 2 BBB MEDICINES B V (NL) 2019-03-13 EP claimed
EP-3395372-A1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM 2-BBB Medicines B.V. (NL) 2018-10-31 EP claimed
US-20180085311-A1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES MIRECA MEDICINES GMBH (DE) 2018-03-29 US claimed
EP-3270889-A1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES Mireca Medicines GmbH (DE) 2018-01-24 EP claimed
WO-2016146669-A1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) 2016-09-22 WO claimed
US-20140227185-A1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM TO-BBB HOLDING B.V. (NL) 2014-08-14 US claimed
EP-2398500-A2 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM TO-BBB Holding B.V. (NL) 2011-12-28 EP claimed
US-20110305751-A1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM TO-BBB HOLDING B.V. (NL) 2011-12-15 US claimed
WO-2010095940-A2 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM TO-BBB HOLDING B.V. (NL) 2010-08-26 WO claimed
EP-3270889-B1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES MIRECA MEDICINES GMBH (DE) 2024-02-07 EP disclosed
WO-2022074181-A1 NANOCARRIER FORMULATIONS FOR INHALATION EnhanX Biopharm Inc. (TW) 2022-04-14 WO disclosed
EP-3395372-B1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM ENHANX BIOPHARM INC (TW) 2022-04-06 EP disclosed
US-20020168327-A1 Treatment of dandruff UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-11-14 US disclosed
US-6451341-B1 ADMINISTERING TO ANIMAL DIETARY SUPPLEMENT COMPRISING BUTYLATED HYDROXYTOLUENE(BHT), BUTYLATED HYDROXYANISOLE(BHA), VITAMIN E, AND B-CAROTENE TO PREVENT SKIN CANCER BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2002-09-17 US disclosed
EP-0514451-B1 DIETARY SUPPLEMENTS COMPRISING VITAMINS AND MINERALS LIFESCIENCE CORP (US) 1997-01-15 EP disclosed
US-5472698-A Mixture of (N-acetyl)-L-serine, N-acetylcysteine and alpha-lipoic acid which promotes ceramide production in skin cells ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) 1995-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10322087-B2 Targeted liposomal delivery of cGMP analogues PDE6C, PDE2A, GMPS PTGS1 131/4885GSTK1 64/4885GLO1 155/4885
US-20110305751-A1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM GSS, GSTO1, SLC7A11 PTGS1 292/4885GSTK1 13/4885GLO1 93/4885
US-20020168327-A1 Treatment of dandruff CYP51A1, ERG28, SREBF1 PTGS1 2480/4885GSTK1 1223/4885GLO1 1274/4885
US-20180085311-A1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES PDE6C, PDE2A, GMPS PTGS1 131/4885GSTK1 71/4885GLO1 166/4885
US-20140227185-A1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM GSS, GSTO1, SLC7A11 PTGS1 292/4885GSTK1 13/4885GLO1 93/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.