Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924716 | 0.95 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3ADRB2 | |
| SCHEMBL15027495 | 0.89 | DNM1 (0.35) | CHRM2CHRM4CHRM1CHRM3ADRB2 | |
| SCHEMBL31323871 | 0.88 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3ADRB2 | |
| SCHEMBL31323883 | 0.88 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3ADRB2 | |
| SCHEMBL15028140 | 0.88 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3ADRB2 | |
| SCHEMBL20924797 | 0.84 | SIGMAR1 (0.39) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL20924796 | 0.82 | CHRM2 (0.35) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL16376199 | 0.81 | CHRM2 (0.32) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL20924799 | 0.76 | DNM1 (0.58) | ALDH1A1MAPT | |
| SCHEMBL15027494 | 0.76 | SIGMAR1 (0.40) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788316-B1 | BRANCHED ALKYL AND CYCLOALKYL TERMINATED BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS INC (US) | 2019-04-24 | — | — | EP | disclosed |