Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 9/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15027494 | 0.92 | SIGMAR1 (0.40) | SIGMAR1DNM1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL15026847 | 0.85 | SIGMAR1 (0.43) | SIGMAR1DNM1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL20924798 | 0.84 | CHRM2 (0.36) | SIGMAR1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL20924799 | 0.81 | DNM1 (0.58) | DNM1NAAAMAPTALDH1A1 | |
| SCHEMBL31226902 | 0.81 | ALDH1A1 (0.46) | SIGMAR1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL20924716 | 0.80 | CHRM2 (0.36) | SIGMAR1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL31226801 | 0.79 | ALDH1A1 (0.42) | SIGMAR1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL20924903 | 0.78 | ALDH1A1 (0.48) | SIGMAR1DNM1SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL20924796 | 0.78 | CHRM2 (0.35) | SIGMAR1DNM1CHRM2CHRM4CHRM1 | |
| SCHEMBL31226765 | 0.78 | SIGMAR1 (0.39) | SIGMAR1MEN1MAPTKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788316-B1 | BRANCHED ALKYL AND CYCLOALKYL TERMINATED BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS INC (US) | 2019-04-24 | — | — | EP | disclosed |