SCHEMBL20927635

SCHEMBL20927635

Cc1ccc(N(c2ccc3c(c2)C(C)(C)c2cc(-c4ccccc4)c4oc5ccccc5c4c2-3)c2ccc3c(c2)C(C)(C)c2cc(-c4ccccc4)c4oc5ccccc5c4c2-3)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.32
▸ CDC14B O60729 1/20 0.32
▸ CDC14A Q9UNH5 1/20 0.32
▸ LMNA P02545 1/20 0.31
▸ ALK Q9UM73 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22389274 0.94 MAPT (0.33) MAPTCDC14BCDC14ALMNA
SCHEMBL22389227 0.93 LMNA (0.32) LMNAALK
SCHEMBL24580610 0.93 — —
SCHEMBL24579948 0.93 — —
SCHEMBL22389130 0.92 ALDH1A1 (0.31) MAPTLMNA
SCHEMBL20927630 0.91 CDC14B (0.33) MAPTCDC14BCDC14AALK
SCHEMBL24580191 0.91 — —
SCHEMBL21785117 0.91 — —
SCHEMBL20927634 0.90 MAPT (0.33) MAPTCDC14BCDC14AALK
SCHEMBL20927669 0.90 CDC14B (0.34) MAPTCDC14BCDC14AALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225195-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2023-07-13 — — US disclosed
US-20230225195-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2023-07-13 — — US disclosed
US-11578063-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-02-14 — — US disclosed
US-20200277284-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-03 — — US disclosed
WO-2019076789-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-04-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200277284-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM MAPT 1878/4885CDC14B 4597/4885CDC14A 4518/4885
US-11578063-B2 Materials for organic electroluminescent devices GPX1, EPCAM, EFNA1 MAPT 2228/4885CDC14B 4688/4885CDC14A 4632/4885
US-20230225195-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES H1-0, H1-2, H1-4 MAPT 834/4885CDC14B 4847/4885CDC14A 4797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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