Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSH | P09668 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92793 | 1.00 | TSHR (0.54) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL19248423 | 1.00 | TSHR (0.54) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL27549297 | 0.94 | TSHR (0.54) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL20269906 | 0.90 | LMNA (0.51) | TSHRCYP3A4ALDH1A1MAPK1HPGD | |
| SCHEMBL27794811 | 0.86 | ESR1 (0.55) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL16732085 | 0.85 | TSHR (0.55) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL28557095 | 0.84 | TSHR (0.51) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL2426331 | 0.84 | TSHR (0.54) | TSHRCYP3A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL31257795 | 0.83 | CYP3A4 (0.55) | TSHRCYP3A4ALDH1A1MAPK1HPGD | |
| SCHEMBL1892061 | 0.83 | MMP8 (0.59) | TSHRCYP3A4ALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019076178-A1 | DEGRADATION TIME CONTROLLABLE AND BREAKING ELONGATION ADJUSTABLE MEDICAL DEGRADABLE POLYURETHANE | 凯斯蒂南京医疗器械有限公司 | 2019-04-25 | — | — | WO | disclosed |
| CN-107072250-A | Paenibacillus and bacillus species mannanases | 丹尼斯科美国公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-103608356-A | Detergent compositions containing bacillus agaradhaerens mannanase and methods of use thereof | DANISCO US INC | 2014-02-26 | — | — | CN | disclosed |
| CN-103534266-A | Detergent compositions comprising GEOBACILLUS caldus (GEOBACILLUS TEPIDAMANS) mannanase and methods of use thereof | DANISCO US INC | 2014-01-22 | — | — | CN | disclosed |
| CN-103502445-A | Detergent compositions containing bacillus sp. mannanase and methods of use thereof | DANISCO US INC | 2014-01-08 | — | — | CN | disclosed |
| CN-102712880-A | Detergent compositions containing geobacillus stearothermophilus lipase and methods of use thereof | DANISCO US INC | 2012-10-03 | — | — | CN | disclosed |
| CN-102712878-A | Detergent compositions containing bacillus subtilis lipase and methods of use thereof | DANISCO US INC | 2012-10-03 | — | — | CN | disclosed |
| CN-102712879-A | Detergent compositions containing thermobifida fusca lipase and methods of use thereof | DANISCO US INC | 2012-10-03 | — | — | CN | disclosed |