Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL649851 | 0.76 | — | — | |
| SCHEMBL4404412 | 0.74 | CYP2D6 (0.46) | CYP2D6CA1CA2CA4PSEN1 | |
| SCHEMBL7953730 | 0.72 | LMNA (0.31) | MAPT | |
| SCHEMBL23838437 | 0.72 | CA1 (0.37) | CA1CA2CA4KMT2AMAPT | |
| SCHEMBL2344622 | 0.72 | CA1 (0.37) | CA1CA2CA4KMT2AMAPT | |
| SCHEMBL24483924 | 0.68 | CA1 (0.34) | CA1CA2CA4KMT2AMAPT | |
| SCHEMBL25958842 | 0.67 | APLNR (0.39) | CYP2D6 | |
| SCHEMBL12826108 | 0.66 | — | — | |
| SCHEMBL2343690 | 0.66 | — | — | |
| SCHEMBL19155702 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019075574-A1 | CONDURITOL AZIRIDINE DERIVATIVES AND USES THEREOF | UNIVERSITY OF SASKATCHEWAN (CA) | 2019-04-25 | — | — | WO | disclosed |